Naproxen caffeine salicylamide rectal suppositories 10. Cefekon H - instructions for use

Suppositories are white or white with a yellowish or creamy tint, torpedo-shaped. There should be no inclusions on the longitudinal section of the suppository; the presence of an air rod or funnel-shaped depression is allowed.

Active ingredients

Release form

Suppositories

Compound

One suppository contains: active ingredients: caffeine - 50 mg, naproxen - 75 mg, salicylamide - 600 mg, excipients: solid fat (Vitepsol, brands H 15, W 35, Supposir, brands NA 15, NAS 50) - until a suppository is obtained weighing 2.20 g.

Indications

as an analgesic for mild to moderate pain syndrome: neuralgia, myalgia, sciatica, lumbago, degenerative diseases of the musculoskeletal system (osteochondrosis, osteoarthritis, ankylosing spondylitis), headache and toothache, migraine, dysmenorrhea (painful menstruation), as an antipyretic: febrile syndrome in colds, infectious, inflammatory diseases.

Contraindications

Hypersensitivity to the components of the drug, peptic ulcer stomach and duodenum (acute phase), complete or incomplete combination bronchial asthma, recurrent polyposis of the nose and paranasal sinuses and intolerance acetylsalicylic acid or other NSAIDs (including a history), hypocoagulation, severe renal and/or liver failure, arterial hypertension, organic diseases of the cardiovascular system, heart failure, blood diseases, edema, pathology of the vestibular apparatus, increased excitability, insomnia , angle-closure glaucoma, childhood(up to 16 years), pregnancy, lactation period.

Precautionary measures

Old age (over 70 years old).

Directions for use and doses

Rectally. The suppository is released from the contour cell packaging and after spontaneous bowel movement or a cleansing enema, 1 suppository is injected deep into the rectum 1-3 times a day. After administering the suppository, you must remain in a horizontal position for 30-40 minutes. The duration of use without consulting a doctor is no more than 5 days when prescribed as an analgesic and 3 days as an antipyretic.

Side effects

Allergic reactions, dizziness, agitation, drowsiness, slowing of the speed of psychomotor reactions, tinnitus, tachycardia, increased blood pressure, thrombocytopenia, agranulocytosis, aplastic anemia, impaired liver and/or kidney function, itching and pain in the rectum.

Overdose

No cases of overdose of Cefekon® N have been reported.

Interaction with other drugs

Naproxen reduces the hypotensive effect of beta-blockers. When used concomitantly, naproxen may cause a decrease in the diuretic effect of furosemide. Naproxen increases the toxicity of phenytoin, sulfonamides, and methotrexate. Salicylamide enhances the effect of indirect anticoagulants, antiplatelet agents, fibrinolytics. Salicylamide increases the risk of developing side effects glucocorticosteroids, mineralocorticosteroids, estrogens with joint use. With the simultaneous use of salicylamide with myelotoxic drugs, the risk of depression of cerebral circulation (hematopoiesis) increases. Caffeine accelerates absorption and enhances the effect of cardiac glycosides, increasing their toxicity. The combined use of caffeine with beta-blockers can lead to mutual suppression of therapeutic effects, with adrenergic bronchodilators - to additional stimulation of the central nervous system and other additive toxic effects.

Cefekon is both an analgesic, antipyretic and anti-inflammatory drug.

Depending on the composition and concentration of active ingredients, two types of this drug are distinguished:

• for children (Cefekon D), where the main component is paracetamol;
• adult (Cefekon N) this type of drug contains naproxen, salicylamide and caffeine.

The drug should be stored at a temperature not exceeding +25 °C in dry, well-ventilated areas. The shelf life is 2 years.

Cefekon D is commercially available and available without a prescription. Purchase of Cefekon N is possible only with a prescription.

Release form

The annotation for the drug states that Cefekon is available in the following forms:

• Tsefekon for children in the form rectal suppositories. They have an oblong shape, white with yellow or brown tints. May contain 50 mg, 100 mg or 250 mg paracetamol. 1 blister contains 5 suppositories. The cardboard package contains 2 blisters;
• Cefekon for adults is also produced in the form of suppositories. White with yellow or light brown tints, oblong in shape. 1 blister contains 5 rectal suppositories. 1 package contains 2 blisters.

Pharmacological properties

Each form of release of the drug has analgesic, analgesic and antipyretic effects. The product directly affects the centers pain, blocking them. At the same time, the components of the drug do not negatively affect the mucous membrane of the gastrointestinal tract and its functioning as a whole.

The action of Cefekon does not lead to significant changes in normal body temperature. The drug is excreted through the kidneys and then through the urethra.

Adhering to the instructions for use of Cefekon, it must be used as an analgesic for:

• osteochondrosis;
• migraine;
• osteoarthritis;
• neuralgia;
• lumbago;
• toothache;
• headaches;
• pain in muscles and joints.

This type of medication will be an effective antipyretic for:

• flu;
• rhinitis;
• pharyngitis;
• tonsillitis;
• tracheitis;
• bronchitis;
• ARVI;
• fever;
• various infectious diseases(measles, rubella, whooping cough, chicken pox);
• reactions to vaccination.

Considering the composition and form of release of the drug, it must be taken as follows:

• Cefekon D. This form of medication was developed specifically for young children who cannot swallow the medicine or who are accompanied by a gag reflex when taking it. Candles must not be cut, broken or divided into parts. The dosage of the drug is determined based on the weight and age of the child.

  A single dose of the drug for children aged 1 to 3 months is 50 mg. If the child’s age is in the range from 3 to 12 months, then it is necessary to administer a suppository with a dosage of 100 mg. At the age of 1 to 3 years, 1-2 100 mg suppositories will be sufficient. Children from 3 to 10 years old are prescribed a 250 mg suppository. At the age of 10–12 years, 2 suppositories of 250 mg are administered. The maximum permissible daily dose is 60 mg/kg. The suppository is carefully inserted into the rectum, having previously lubricated anus baby cream or Vaseline. It is better to do this after emptying the stomach or an enema.

• Cefekon N. This form of the drug is approved for use in children over 16 years of age and adults. The suppository is carefully inserted into the rectum, preferably after a bowel movement or enema. Depending on the symptoms of the disease, from 1 to 3 suppositories can be used per day. After administering the suppository, it is advisable for the patient to remain in bed for some time and try to move as little as possible.

Contraindications, overdose and side effects

Before starting to use Cefekon, you should familiarize yourself with the list of contraindications. These include:

• stomach and duodenal ulcers;
• chronic kidney and liver diseases;
• various pathologies of the cardiovascular system;
• bronchospasm;
• arterial hypertension;
• angle-closure glaucoma;
• insomnia;
• advanced age;
• hypersensitivity to the components of the drug;
• period of pregnancy and lactation.

In rare cases, the drug may cause side effects such as:

• tachycardia;
• Quincke's edema;
• skin rash;
• nausea and vomiting;
• anemia;
• pain in the stomach;
• dizziness;
• noise in ears;
• increased fatigue.

As a result of significantly exceeding the permissible dosage, overdose symptoms may occur, such as:

• dysfunction of the liver and kidneys;
• headache;
• constipation or, conversely, diarrhea;
• frequent urination;
• heart failure;
• slow reaction;
• a sharp increase in blood pressure;
• convulsions.

If one or more of the above symptoms appear, you must stop taking medicine and provide appropriate symptomatic therapy.

During pregnancy and lactation

All forms of Cefekon are contraindicated for consumption throughout the entire period of pregnancy and during breastfeeding.

Medicines with a similar effect include:

• Paracetamol;
• Efferalgan;
• all forms of Panadol;
• Febricet;
• Sanidol;
• Ifimol;
• Daleron;
• all forms of Tylenol.

Efficiency and reviews

Cefekon is an excellent medicinal solution for high temperature and the first symptoms of ARVI in children and adults. The pediatric form of the medicine allows you to use the drug starting from 1 month. At the same time, Cefekon begins to act within half an hour after administration.

Many parents note positive dynamics in children after using these rectal suppositories. The temperature quickly returns to normal, general state the child is improving.

The adult form of the drug, in addition to fever, copes well with pain syndromes of various localizations.

orvistop.ru

pharmachologic effect

Latin name

Release form

Rectal suppositories. 5 suppositories in a blister pack. Two blister packs together with instructions for medical use of the drug are placed in a cardboard box.

Analogs by release form

Cefekon d rectal suppositories for children 50 mg 10 pcs.

Nizhpharm, Russia

Cefekon d rectal suppositories for children 100 mg 10 pcs.

Nizhpharm, Russia

Children's Panadol rectal suppositories 125 mg, 10 pcs.

GlaxoSmithKline, UK

Cefekon d rectal suppositories for children 250 mg 10 pcs.

Nizhpharm, Russia

Efferalgan rectal suppositories 80 mg 12 pcs.

UPSA SAS, France

show more

pharmachologic effect

Cefekon® N is a combined drug that has analgesic, antipyretic and anti-inflammatory effects.

Naproxen and salicylamide are non-steroidal anti-inflammatory drugs (NSAIDs), the mechanism of action of which is associated with inhibition of prostaglandin synthesis and an effect on the thermoregulatory center in the hypothalamus.

Caffeine has a psychostimulant, analeptic and antispasmodic effect on smooth muscles.

Analogues in composition

Paracetamol tablets 500 mg 10 pcs.

Pharmstandard, Russia

Pills

Paracetamol suspension for oral administration strawberry 120 mg/5 ml 100 g

Pharmstandard, Russia

Suspension

Paracetamol tablets 500 mg 20 pcs.

Pharmstandard, Russia

Pills

Paracetamol tablets 200 mg, 10 pcs.

Tatkhimpharmaceuticals,

Pills

Paracetamol extratab 500 mg + 150 mg tablets 10 pcs.

Obolenskoye FP, Russia

Pills

Paracetamol renewal tablets 500 mg 20 pcs.

PFC update,

Pills

Indications

Indications

Cefekon N is used as an analgesic for mild to moderate pain: neuralgia, myalgia, sciatica, lumbago, degenerative diseases of the musculoskeletal system (osteochondrosis, osteoarthritis, ankylosing spondylitis), headache and toothache, migraine, primary algodismenorrhea.

Cefekon N is used as an antipyretic: febrile syndrome in colds, infectious, inflammatory diseases.

Contraindications

Contraindications

Hypersensitivity to the components of Cefekon N, peptic ulcer of the stomach and duodenum (acute phase), bleeding, severe renal and/or liver failure, arterial hypertension, organic diseases of the cardiovascular system, chronic heart failure, increased excitability, insomnia, closed-angle glaucoma, bronchial obstruction (including caused by taking NSAIDs), elderly and children (up to 16 years) age, pregnancy, breastfeeding period.

special instructions

special instructions

If itching or discomfort appears in the rectum, it is necessary to administer an enema with sunflower oil (1 tablespoon) and temporarily stop using the drug.

Compound

One suppository contains:

active ingredients: caffeine - 50 mg, naproxen - 75 mg, salicylamide - 600 mg,

excipients: solid fat (Vitepsol, brands H 15, W 35, Supposir,

grades NA 15, NAS 50) - until a suppository weighing 2.20 g is obtained.

Directions for use and doses

Directions for use and doses

Cefekon N is used rectally (deeply), after a cleansing enema or spontaneous bowel movement, 1 supp. 1-3 times a day. After administering the suppository, it is necessary to maintain a horizontal position for 30-40 minutes.

The duration of taking Cefekon N without consulting a doctor is no more than 5 days when prescribed as an analgesic and 3 days as an antipyretic.

Side effects

Side effects

Side effects are mild in severity and do not require cessation of therapy or any medical manipulation: allergic reactions, dizziness, agitation, drowsiness, slowing of the speed of psychomotor reactions, tinnitus, tachycardia, increased blood pressure, thrombocytopenia, granulocytopenia, aplastic anemia, dysfunction liver and/or kidneys, itching and pain in the rectum.

Drug interactions

Drug interactions

The hypotensive effect of ACE inhibitors and beta-blockers is reduced when taking Cefekon N.

When taken with sulfonylurea derivatives (oral hypoglycemic agents, anticoagulants), it enhances their effect.

Check the interaction of other drugs with Cefekon N

Add

The drugs you have chosen

clear all

Check interaction

&lsaquo, Back to choosing medications

Do not stop taking the drug without consulting your doctor!

We under no circumstances encourage you to self-medicate or diagnose yourself or your loved ones based on the data in our directory. All information is presented for informational purposes only, to make it easier for you to understand what exactly is bothering you and which specialist doctor you should contact.

Overdose

Overdose

If an overdose occurs, side effects may appear and intensify: bronchospasm, tachycardia, heart failure, dizziness, pain and itching in the rectum, increased blood pressure, dizziness. Symptoms such as diarrhea, tremor, hyperthermia, ringing in the ears, arrhythmias, agitation, drowsiness, frequent urination, irritability, seizures, anxiety, confusion, gastrointestinal bleeding, dehydration, headache, delirium, disorientation are also possible. tactile sensitivity.

It is necessary to stop taking the drug and carry out symptomatic therapy, which should be aimed at maintaining heart activity and reducing blood pressure. You may experience discomfort or itching in the rectum. In this case, you should administer an enema with sunflower oil.

Storage conditions

Storage conditions

In a place protected from light, at a temperature of 2-25°C.

Best before date

Best before date

Possible product names

• Tsefekon n rectal suppositories x 10
• Cefekon n n10 supp
• Tsefekon n10 supp rect
• Tsefekon n rectal suppositories, 10 pcs.
• Tsefekon n supp rect n10

Certificates

Certificates (1)

medik0ff.ru

All categories Medicines Obstetrics, gynecology Medicines for the treatment of others gynecological diseases Medicines for the treatment of gynecological infections Medicines for the treatment of thrush Medicines for the treatment of infertility using IVF Medicines for the treatment of menopause Medicines for the treatment of trichomoniasis and malaria Contraceptives Means for increasing the tone of the uterus Anesthesia, resuscitation Local painkillers Nutrition in intensive care Solutions for anesthesia Anesthesia Antibiotics Antibiotics Other antimicrobial drugs Antituberculosis drugs Ecoantibiotics Blood diseases Hemostatic drugs Anemia drugs Anticoagulants Hematopoietic stimulants Pain, temperature Medicines hormones-corticosteroids Medicines for relief pain and temperature Painkillers Medicines for the treatment of pain and spasms Vitamins Vitamin preparations Vitamins Minerals Multivitamins Eyes Other eye treatments Medicines for glaucoma Painkillers for the eyes Antiviral agents for the treatment of eyes Means for the treatment of allergies, redness Means for the treatment of eye infections and inflammations Means for the treatment of cataracts Worms, lice, scabies Medicines for getting rid of scabies Medicines for worms Medicines for getting rid of lice Homeopathic remedies Diabetes Vitamins and dietary supplements for diabetics Hypoglycemic drugs Diabetic syringe pens Needles, lancets and syringes for diabetics Insulins Medicines for the treatment of complications of diabetes Nutrition for diabetics Diagnostic tools Medicines for getting rid of hemorrhoids Medicines for immune system Medicines for the genitourinary system Medicines to reduce the tone of the uterus Medicines for the treatment of diseases of the respiratory system Medicines for the treatment of oncology Medicines for therapy cardiovascular diseases Medicines for the treatment of endocrinological diseases Treatment of allergies Disinfectants Nutrient mixtures Nutritional supplements(dietary supplements) Drugs for the treatment of the stomach, intestines, liver Drugs for the treatment of ENT organs Drugs for the treatment of neurological, psychiatric diseases Drugs for the treatment of trichomoniasis and malaria Antiviral drugs Antifungal drugs Various means Products for treating skin Products for treating poisoning Products for treating the oral cavity Products for normalizing metabolism

medic.ru

Composition and release form

Cefekon for children is available only in the form of suppositories. Torpedo-shaped suppositories are creamy white or yellowish white in color. The drug is available in several variations:

• 50 mg;
• 100 mg;
• 250 mg.

The product contains paracetamol as an active substance. This is a well-known non-steroidal anti-inflammatory drug that can eliminate pain and reduce fever.

There is only one auxiliary component - vitepsol. This substance is the basis for the manufacture of suppositories. Therefore, we can say that only paracetamol “works” in Cefekon D suppositories. The lightweight composition allows the medicine to be effective and not injure the child’s body.

Important! The drug begins to act 15-30 minutes after use. The product gradually reduces fever, which helps avoid fainting.

The description from the manufacturer states that the drug can be used to get rid of fever (temperature) after vaccination. Only in such a situation are Cefekon suppositories allowed for children under 3 months. But suppositories can only be used once after vaccination. Despite its safe composition, the medicine is not used to treat newborns. What do suppositories help with?

General indications for use:

• diseases the course of which is accompanied by elevated temperature (ARVI, influenza, various infections);
• pain syndromes of low or moderate intensity.

Cefekon D for children can be used to relieve toothache or headache, burns and severe injuries. The drug is also used to relieve muscle discomfort. It is worth understanding that this medicine is not able to cure the disease, it only fights the symptoms. Therefore, suppositories can be safely included in the complex therapy of viral and infectious pathologies.

Over time, the medication is able to completely relieve pain, which is also its great advantage.

Contraindications

The drug is prohibited for use in children with individual intolerance to the active substance, as well as in patients under 1 month of age. It should be used with caution by people with diseases of the excretory system (liver, kidneys). The medicine is not recommended for use in patients with glucose enzyme deficiency and blood diseases (leukopenia, anemia).

Important! Candles have no effect negative influence on the duodenum and stomach, so they can be used for vomiting.

People with Gilbert's syndrome also need to use Cefekon with great caution.

Before using Cefekon suppositories for children, the instructions must be studied by parents. Suppositories can be used only after an enema or natural bowel movement.

You can use a regular enema for an enema. warm water or a soothing solution with chamomile.

Cefekon D instructions for use

Duration of treatment: 5 days as an anesthetic, 3 days to get rid of fever. If after a week the desired effect does not occur, then you need to contact a specialist. The course of treatment can also be extended according to the doctor’s instructions.

Important! Suppositories cannot be held in your hands for a long time; they must be administered immediately after taking them out of the package. The candles begin to melt due to body temperature. Therefore, they also quickly dissolve in the rectum.

A small child (up to 3 months) can be given 1 suppository at a minimum dose of 50 mg. After using the candle, you need to carefully monitor the baby’s well-being, since there is a high risk of allergic reactions on the skin or mucous membranes.

Side effects

You need to be careful with Cefekon suppositories, since many children experience side effects after using them. If the child feels unwell after the first use of suppositories, then the course of treatment should be suspended.

Common side effects that are normal:

• nausea;
• diarrhea;
• stomach ache.

It is not normal for a child to start vomiting or become anemic. You should also be wary of signs of allergies: itching, swelling, rashes. The manufacturer does not provide data on overdose, so you need to be careful.

Advice! Use suppositories correctly, carry out all hygiene procedures before administering suppositories and follow the dosage.

Storage conditions, cost and analogues

It is imperative to follow the rules for storing Tsefekon suppositories. They should be kept in a dry place out of the reach of children. Store for no more than 2 years at a temperature not exceeding 20 degrees.

The price of the drug is budget, especially for antipyretics. The medicine can be purchased for 50-100 rubles in almost any pharmacy. It is also sold on the Internet. Before ordering a drug, you need to carefully look at its photo. Many virtual stores sell counterfeit drugs - dummies.

Cefekon candles do not have many analogues:

• Paracetamol in suppository form ( complete analogue drug for children Tsefekon) - from 40 rubles.
• Paracetamol-Alpharm ( this remedy can be used by children, adolescents and adults) - from 45 rubles.
• Children's Panadol (candles for children and adults) - from 70 rubles.

All analogues of cefekon suppositories have almost the same effect. They relieve pain syndromes and reduce temperature.

Cefekon D is a drug that really needs to be kept in the medicine cabinet if there are small children in the house. The product has a very good composition, mild effect and minimum contraindications.

pro-children.com

Tsefekon suppositories for adults are prescribed as an anesthetic for pain of moderate to mild severity. Indications include, in particular, sciatica, myalgia, neuralgia, disorders in the functioning of the musculoskeletal system of a degenerative-dystrophic nature, lumbago, osteoarthritis, osteochondrosis, ankylosing spondylitis. The medicine is also recommended for primary algodismenorrhea, migraine, toothache and headache. The drug is also indicated as an antipyretic to relieve febrile syndrome during colds, inflammatory and infectious pathologies.

Medicine "Cefekon" (suppositories). Contraindications

The medication is not recommended for hypersensitivity to components, stomach ulcers, bleeding, arterial hypertension. Contraindications also include severe hepatic or renal failure. The remedy is not recommended for increased excitability, pathologies of the cardiovascular system of an organic nature, or insomnia. Contraindications include angle-closure glaucoma and bronchial obstruction. The medicine is not prescribed for the elderly and children (under 16 years of age). The medication "Cefekon" (suppositories) is also not recommended during pregnancy and lactation.

Pharmacological activity

The mechanism of action of the drug is due to medicinal properties its components. Salicylamide and naproxen - active substances - are included in the group of NSAIDs. Their mechanism of action is based on the effect on the thermoregulation center located in the hypothalamus. Caffeine has a psychostimulating, antispasmodic and analeptic effect on smooth muscles. This component also has a stimulating effect on striated muscles. Caffeine also reduces platelet aggregation and releases mast cells histamine.

Means "Cefekon" (suppositories). Side effects

When using the drug, it is possible to develop an allergy. In some cases, increased excitability or drowsiness, dizziness, and tinnitus appear. Some patients experience slowing of psychomotor reactions, tachycardia, thrombocytopenia, increased blood pressure, aplastic anemia, pain and itching in the rectum, and disorders of renal and liver function.

The drug "Cefekon" (suppositories). Mode of application

Suppositories are administered rectally, deep into the rectum. Before use, you should give a cleansing enema. The recommended dosage is 1 suppository no more than three times a day. After use, you should remain in a horizontal position for at least thirty to forty minutes. The course of therapy without consulting a specialist is no more than five days as an anesthetic and no more than three days as an antipyretic. If symptoms persist, you should visit a doctor.

Means "Cefekon" (suppositories). special instructions

If rectal discomfort or itching occurs, an enema with sunflower oil and temporary discontinuation of the medication are recommended. The drug is valid for twenty-four months. Consultation with a doctor before use is required.

www.syl.ru

In this article you can find instructions for use medicinal product Tsefekon D and N. Reviews of site visitors - consumers of this medicine, as well as the opinions of specialist doctors on the use of Cefekon D and N in their practice are presented. We kindly ask you to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation. Analogues of Cefekon D and N in the presence of existing structural analogues. Use to treat pain and reduce fever in adults, children, as well as during pregnancy and breastfeeding. Composition of an antipyretic drug.

Tsefekon D and N- has an analgesic and antipyretic effect. Blocks cyclooxygenase in the central nervous system, affecting pain and thermoregulation centers. At the site of inflammation, cellular peroxidases neutralize the effect of paracetamol on cyclooxygenase, which explains the lack of significant anti-inflammatory effect.

The drug does not have negative influence on water-electrolyte metabolism (does not lead to sodium and water retention) and the gastrointestinal mucosa.

Compound

Paracetamol + excipients (Cefekon D).

Naproxen + Caffeine + Salicylamide + excipients (Cefekon N).

Pharmacokinetics

Fast and in high degree absorbed from the gastrointestinal tract. Plasma protein binding - 15%. Penetrates the blood-brain barrier (BBB). Metabolized in the liver; 80% reacts with glucuronic acid and sulfates to form inactive metabolites; 17% undergoes hydroxylation to form active metabolites, which are then conjugated with glutathione to form inactive metabolites. With a lack of glutathione, these metabolites can block the enzyme systems of hepatocytes and cause their necrosis. Within 24 hours, 85-95% of paracetamol is excreted by the kidneys in the form of glucuronides and sulfates, 3% unchanged.

In newborns of the first 2 days of life and in children aged 3-10 years, the main metabolite of paracetamol is paracetamol sulfate, in children 12 years and older - conjugated glucuronide. There is no significant age-related difference in the rate of elimination of paracetamol and in the total amount of the drug excreted in the urine.

Indications

As an analgesic for mild to moderate pain:

• neuralgia;
• myalgia;
• sciatica;
• lumbago;
• degenerative-dystrophic diseases of the musculoskeletal system (osteochondrosis, osteoarthritis, ankylosing spondylitis);
• headache, migraine;
• toothache;
• primary algodismenorrhea.

As an antipyretic:

• febrile syndrome with ARVI, influenza, other colds, childhood infections, post-vaccination reactions and other conditions accompanied by an increase in body temperature.

Release forms

Rectal suppositories for children 50 mg, 100 mg and 250 mg (Cefekon D).

Rectal suppositories (Cefekon N).

Instructions for use and method of use

The drug is administered rectally. Suppositories are introduced into the child’s rectum after a cleansing enema or spontaneous bowel movement.

The dosage regimen is set depending on age and body weight. The average single dose is 10-15 mg/kg of the child’s body weight. The drug in a single dose is administered 2-3 times a day, every 4-6 hours. The maximum daily dose of the drug should not exceed 60 mg/kg body weight.

When using the drug as an antipyretic, the duration of treatment is 3 days; as a pain reliever - 5 days. If necessary, the doctor may extend the course of treatment.

The drug should be used after a cleansing enema or spontaneous bowel movement.

Prescribe 1 suppository 1-3 times a day. The suppository is injected deep into the rectum, after which the patient must remain in bed for 30-40 minutes.

Duration of use as an anesthetic is no more than 5 days; as an antipyretic - no more than 3 days.

Side effect

• nausea, vomiting;
• stomach ache;
• rash on the skin and mucous membranes;
• hives;
• Quincke's edema;
• dizziness;
• excitation;
• drowsiness;
• noise in ears;
• slowing down the speed of psychomotor reactions;
• tachycardia;
• anemia, thrombocytopenia, leukopenia, agranulocytosis;
• with long-term use in high doses, the development of hepatotoxic and nephrotoxic (interstitial nephritis and papillary necrosis) effects, hemolytic anemia, aplastic anemia, methemoglobinemia, pancytopenia is possible.

Contraindications

• age up to 1 month (for the drug Cefekon D), childhood and adolescence up to 16 years (for the drug Cefekon N);
• peptic ulcer of the stomach and duodenum in the acute phase;
• bleeding;
• severe renal or liver failure;
• arterial hypertension;
• organic diseases of the cardiovascular system;
• chronic heart failure;
• increased excitability;
• insomnia;
• angle-closure glaucoma;
• bronchospasm (including those caused by taking non-steroidal anti-inflammatory drugs);
• elderly age;
• pregnancy;
• lactation (breastfeeding);
• hypersensitivity to paracetamol.

Use during pregnancy and breastfeeding

Cefekon N is contraindicated for use during pregnancy and lactation.

Use in children

Cefekon D is contraindicated in children under 1 month of age (including newborns), Cefekon N is contraindicated in children and adolescents under 16 years of age.

special instructions

The patient should be warned about the need to consult a doctor if fever persists for more than 3 days and pain persists for more than 5 days.

Concomitant use with other paracetamol-containing drugs should be avoided, because this may cause an overdose of paracetamol.

When using the drug Cefekon D and N for more than 5-7 days, peripheral blood counts and the functional state of the liver should be monitored. Paracetamol distorts laboratory results in the quantitative determination of glucose and uric acid in plasma.

Drug interactions

Inducers of microsomal oxidation in the liver (phenytoin, ethanol (alcohol), barbiturates, flumecinol, rifampicin, phenylbutazone, tricyclic antidepressants), ethanol, hepatotoxic drugs increase the production of hydroxylated active metabolites, which makes it possible to develop severe intoxication even with a slight overdose.

Microsomal oxidation inhibitors (cimetidine) reduce the risk of hepatotoxicity.

When taken simultaneously with salicylates, the likelihood of developing nephrotoxicity increases.

When used together with paracetamol, the toxic effects of chloramphenicol are enhanced.

When used together with paracetamol, the effect of anticoagulants is enhanced indirect action and the effectiveness of uricosuric drugs decreases.

Analogues of the drug Cefekon

Structural analogues of the active substance:

• Aldolor;
• Apap;
• Acetaminophen;
• Daleron;
• Children's Panadol;
• Children's Tylenol;
• Ifimol;
• Calpol;
• Xumapar;
• Lupocet;
• Mexalen;
• Pamol;
• Panadol;
• Panadol Junior;
• Paracetamol;
• Perfalgan;
• Passer;
• Children's walker;
• Sanidol;
• Strimol;
• Tylenol;
• Tylenol for babies;
• Febricet;
• Efferalgan.

instrukciya-otzyvy.ru

Source: kashelisopli.com

Cefekon is both an analgesic, antipyretic and anti-inflammatory drug.

Depending on the composition and concentration of active ingredients, two types of this drug are distinguished:

• for children (Cefekon D), where the main component is paracetamol;
• adult (Cefekon N) this type of drug contains naproxen, salicylamide and caffeine.

The drug should be stored at a temperature not exceeding +25 °C in dry, well-ventilated areas. The shelf life is 2 years.

Cefekon D is commercially available and available without a prescription. Purchase of Cefekon N is possible only with a prescription.

Release form

The annotation for the drug states that Cefekon is available in the following forms:

• Cefekon for children in the form of rectal suppositories. They have an oblong shape, white with yellow or brown tints. May contain 50 mg, 100 mg or 250 mg paracetamol. 1 blister contains 5 suppositories. The cardboard package contains 2 blisters;
• Cefekon for adults is also produced in the form of suppositories. White with yellow or light brown tints, oblong in shape. 1 blister contains 5 rectal suppositories. 1 package contains 2 blisters.

Pharmacological properties

Each form of release of the drug has analgesic, analgesic and antipyretic effects. The product directly affects pain centers, blocking them. At the same time, the components of the drug do not negatively affect the mucous membrane of the gastrointestinal tract and its functioning as a whole.

The action of Cefekon does not lead to significant changes in normal body temperature. The drug is excreted through the kidneys and then through the urethra.

Indications for use

Adhering to the instructions for use of Cefekon, it must be used as an analgesic for:

• osteochondrosis;
• migraine;
• osteoarthritis;
• neuralgia;
• lumbago;
• toothache;
• headaches;
• pain in muscles and joints.

This type of medication will be an effective antipyretic for:

• flu;
• rhinitis;
• pharyngitis;
• tonsillitis;
• tracheitis;
• bronchitis;
• ARVI;
• fever;
• various infectious diseases (measles, rubella, whooping cough, chicken pox);
• reactions to vaccination.

Considering the composition and form of release of the drug, it must be taken as follows:

• Cefekon D. This form of medication was developed specifically for young children who cannot swallow the medicine or who are accompanied by a gag reflex when taking it. Candles must not be cut, broken or divided into parts. The dosage of the drug is determined based on the weight and age of the child.

  A single dose of the drug for children aged 1 to 3 months is 50 mg. If the child’s age is in the range from 3 to 12 months, then it is necessary to administer a suppository with a dosage of 100 mg. At the age of 1 to 3 years, 1-2 100 mg suppositories will be sufficient. Children from 3 to 10 years old are prescribed a 250 mg suppository. At the age of 10–12 years, 2 suppositories of 250 mg are administered. The maximum permissible daily dose is 60 mg/kg. The suppository is carefully inserted into the rectum, after lubricating the anus with baby cream or Vaseline. It is better to do this after emptying the stomach or an enema.

• Cefekon N. This form of the drug is approved for use in children over 16 years of age and adults. The suppository is carefully inserted into the rectum, preferably after a bowel movement or enema. Depending on the symptoms of the disease, from 1 to 3 suppositories can be used per day. After administering the suppository, it is advisable for the patient to remain in bed for some time and try to move as little as possible.

Contraindications, overdose and side effects

Before starting to use Cefekon, you should familiarize yourself with the list of contraindications. These include:

• stomach and duodenal ulcers;
• chronic kidney and liver diseases;
• various pathologies of the cardiovascular system;
• bronchospasm;
• arterial hypertension;
• angle-closure glaucoma;
• insomnia;
• advanced age;
• hypersensitivity to the components of the drug;
• period of pregnancy and lactation.

In rare cases, the drug may cause side effects such as:

• tachycardia;
• Quincke's edema;
• skin rash;
• nausea and vomiting;
• anemia;
• pain in the stomach;
• dizziness;
• noise in ears;
• increased fatigue.

As a result of significantly exceeding the permissible dosage, overdose symptoms may occur, such as:

• dysfunction of the liver and kidneys;
• headache;
• constipation or, conversely, diarrhea;
• frequent urination;
• heart failure;
• slow reaction;
• a sharp increase in blood pressure;
• convulsions.

If one or more of the above symptoms appear, you must stop taking the drug and carry out appropriate symptomatic therapy.

During pregnancy and lactation

All forms of Cefekon are contraindicated for consumption throughout the entire period of pregnancy and during breastfeeding.

Analogues

Medicines with a similar effect include:

• Paracetamol;
• Efferalgan;
• all forms of Panadol;
• Febricet;
• Sanidol;
• Ifimol;
• Daleron;
• all forms of Tylenol.

Efficiency and reviews

Cefekon is an excellent medicinal solution for high fever and the first symptoms of ARVI in children and adults. The pediatric form of the medicine allows you to use the drug starting from 1 month. At the same time, Cefekon begins to act within half an hour after administration.

Many parents note positive dynamics in children after using these rectal suppositories. The temperature quickly returns to normal, and the child’s general condition improves.

The adult form of the drug, in addition to fever, copes well with pain syndromes of various localizations.

Cefekon N- a combined drug that has analgesic, antipyretic and anti-inflammatory effects. Naproxen and salicylamide are non-steroidal anti-inflammatory drugs, the mechanism of action of which is associated with inhibition of prostaglandin synthesis and an effect on the thermoregulatory center in the hypothalamus. Caffeine has a psychostimulant, analeptic and antispasmodic effect on smooth muscle, stimulates striated muscle, reduces platelet aggregation and releases histamine from mast cells.

Indications for use:
Cefekon N used as an anesthetic for mild to moderate pain syndromes: neuralgia, myalgia, sciatica, lumbago; degenerative-dystrophic diseases of the musculoskeletal system (osteochondrosis, osteoarthritis, ankylosing spondylitis); headache, toothache, migraine; primary algodismenorrhea; as an antipyretic: febrile syndrome in colds, infectious, inflammatory diseases.

Mode of application:
Cefekon N applied rectally. The suppository is released from the contour cell packaging and after spontaneous bowel movement or a cleansing enema, 1 suppository is injected deep into the rectum 1-3 times a day. After administering the suppository, you must remain in a horizontal position for 30-40 minutes.
The duration of use without consulting a doctor is no more than 5 days when prescribed as an analgesic and 3 days as an antipyretic.

Side effects:
Side effects when using the drug Cefekon N have a mild severity and do not require cessation of therapy or any medical manipulations: allergic reactions, dizziness, agitation, drowsiness, slowing of the speed of psychomotor reactions, tinnitus, tachycardia, increased blood pressure, thrombocytopenia, granulocytopenia, aplastic anemia, impaired liver function and/or kidneys; itching and pain in the rectum.

Contraindications:
Contraindications to the use of the drug Cefekon N are: hypersensitivity to the components of the drug, peptic ulcer of the stomach and duodenum (exacerbation phase), bleeding, severe renal and/or liver failure, arterial hypertension, organic diseases of the cardiovascular system, chronic heart failure, increased excitability, insomnia, angle-closure glaucoma, broncho-obstruction (incl.

including due to the use of non-steroidal anti-inflammatory drugs), elderly and children (up to 16 years) age, pregnancy, lactation.

Pregnancy:
A drug Cefekon N Contraindicated for use during pregnancy or breastfeeding.

Interaction with other drugs:
Cefekon N reduces the hypotensive effect of beta-blockers, ACE inhibitors; enhances the effect of anticoagulants, oral hypoglycemic agents - sulfonylurea derivatives.

Overdose:
Use of the drug Cefekon N in recommended doses does not lead to overdose. In case of an overdose of the drug, the possible occurrence and intensification of the described side effects: dizziness, tachycardia, increased blood pressure, bronchospasm, heart failure, impaired liver and kidney function, itching and pain in the rectum. As well as anxiety, agitation, motor restlessness, confusion, delirium, dehydration, arrhythmias, hyperthermia, increased frequency of urination, headache, increased tactile or pain sensitivity, tremor, ringing in the ears, convulsive attacks, disorientation, irritability, drowsiness, diarrhea, gastrointestinal bleeding. Treatment: discontinuation of the drug, symptomatic therapy aimed at supporting cardiac activity and lowering blood pressure. If itching or discomfort appears in the rectum, it is necessary to administer an enema of sunflower oil.

Storage conditions:
In a dry, cool place, protected from light and out of reach of children.

Release form:
Cefekon N rectal suppositories. 5 suppositories in a blister pack; one or two blister packs along with instructions for medical use of the drug in a cardboard box.

Compound:
One suppository Cefekon N contains
active substance: naproxen 0.075 g, caffeine 0.05 g, salicylamide 0.6 g;
excipient: vitepsol - sufficient amount to obtain a suppository weighing from 2.09 to 2.31 g.

Additionally:
If itching or discomfort occurs in the rectum, you should administer 15 ml of sunflower oil (1 tablespoon) rectally and temporarily stop using the drug.